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ESE News

Here's what's happening in Electrical & Systems Engineering

When molecules move and rotate, they don’t always do so symmetrically. Rather, they can wobble more in certain directions, represented here by elliptical cones of different sizes in cyan. A new theoretical framework developed by Matthew Lew is set to shake up how scientists measure and interpret wobbly molecular motion. (Image courtesy of Matthew Lew)

Wobbly molecules get a closer look

Matthew Lew introduced a detailed theoretical framework that allows scientists to describe and measure how biomolecules move more accurately.

08.09.2024

Time-lapse single-molecule orientation-localization microscopy (SMOLM) of amyloid beta (Aβ42) fibrils undergoing remodeling, taken over 10 minutes, shown as a multi-colored mosaic. Transiently binding and flashing Nile blue (NB) molecules enable the nanoscale architectures of growing and decaying regions in fibrils to be visualized into these rainbow streams

WashU researchers shine light on amyloid architecture

Lew lab’s innovative microscopy charts amyloid beta’s underlying structure could yield insight into neurodegenerative disease.

07.19.2024

Visual comparison of matched, mismatched and adapted (proposed) deep learning models in PnP-ADMM for the phase retrieval problem. The mismatched model is trained on pathology images instead of faces (matched). The proposed method applies domain adaptation to the mismatched model to restore a high-quality image, comparable in quality to the results achieved using the matched model, with fewer than 1% of the number of images required for training. (Credit: Kamilov lab)

Deep learning models can be trained with limited data

Ulugbek Kamilov, graduate students, develop method that could reduce errors in computational imaging.

07.10.2024

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